Malaria N° 1 - Subjects N° 5

TREATMENT REGIMENS FOR MALARIA AS A FUNCTION OF LEVEL OF CHEMORESISTANCE IN AFRICA
by L. Mashako Mamba

SUMMARY
Malaria is still the most important public health problem in most tropical countries.
Africa is more particularly concerned for according to the WHO estimates in 1988, of the hundred and ten million annual cases of malaria reported worldwide, ninety million came from Africa south of Sahara where malaria comes first among the causes of morbidity and mortality in children under the age of 5 years...

TREATMENT REGIMENS FOR MALARIA AS A FUNCTION OF LEVEL OF CHEMORESISTANCE IN AFRICA
by O.J. Ekanem

SUMMARY
Tropical Africa bears of the brunt of the world's malaria probleme as over 80 % of all malaria cases and death occur in Africa. Chloroquine resistance Plasmodium falciparum (CRPF) has now spread to all countries in Africa south of the Sahara since it was first reported in East Africa (Kenya and Tanzania) in 1979.
By 1983, CRPF was reported in 9 countries in East and Central Africa, by 1989 it was reported in at least 29 countries in all parts of Africa. CRPF has also increased in frequency and intensity throughout Africa. The frequency of CRPF varies between 10 % and 90 % in various areas in Africa with intensity measured by RIII rates varying between 5.9 % and 8.5 % in Nigeria to 25 % in Kenya and 33.1 % in Malawi...