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Malaria N 9 - Subject N 10

K. Marsh

Severe malaria accounts for a large part of the paediatric case load in many African hospitals. It should be suspected as a cause for admission in any severely ill child. Complex definitions have been used for research purposes but for good clinical practice a set of simple clinical criteria allow a useful division of children with malaria into three groups:

The successful management of severe malaria requires appropriate initial assessment and resuscitation followed by parenteral anti-malarial therapy and the of specific complications. Key issues discussed in this paper include the management of metabolic acidosis, hypoglycaemia, severe anaemia, convulsions and co-existent bacterial infections.

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